First Translational Articulation meeting of the IMPACT center of excellence: The research determination connected to clinical practice and society

Deepening the different lines of research of the new IMPACT basal center and promoting translational collaboration among team members was the objective of the first translational articulation meeting of the IMPACT center of excellence, held on June 30, with the presence of the National Agency for Research and Development (ANID).   

The meeting was led by the director of IMPACT and researcher of the Universidad de los Andes, Maroun Khoury, and Miguel Rebolledo, manager of the unit, and counted with the participation of the alternate director of the Center and coordinator of the AI-BIO line, René Botnar, who is also professor of Cardiovascular Imaging at King’s College London and academic of the Pontificia Universidad Católica de Chile.   

This initiative was very positive for Nelson Osses, associate researcher at IMPACT and academic at the Catholic University of Valparaiso. “These are important activities to have a holistic view of the Center. It allows us to understand how the different programs contribute to IMPACT’s overall development and the contribution of the different lines of research. In addition, it is a useful instance to align the research that each one carries out with IMPACT’s objectives.” In personal terms, he said that this meeting allowed him “to learn about some specific lines of research of the different programs, to sound out possibilities of collaboration, to see the options of access to some equipment and to talk about what we are doing in terms of IMPACT”, he explained.  

IMPACT’s director, Maroun Khoury, pointed out that these meetings are fundamental for defining the Center’s mission and aligning with its future projection. “We agree that all the research that will be done at the Center will have a direct link to clinical practice. IMPACT is not only a center with translational aspirations; we will develop, together with our clinical team, technologies including diagnostic markers and advanced therapies to solve clinical needs that are still unmet today,” he said.   

 On the other hand, the manager of IMPACT, Miguel Rebolledo, affirmed that it is not possible “to face the challenges that we have set ourselves without the articulation of the different specialties that the center has, which is why this conference undoubtedly helped to forge the personal, scientific and clinical ties that will make it possible to bring the new medical and therapeutic solutions that are being developed to those who matter to us, the people,” he explained. 

The medicine of the future 

The IMPACT center has four lines of research in line with the latest advances in medicine, which were presented at the articulation meeting by the coordinators of each area. The Biomedical Research and Development Program (BioRed), in charge of IMPACT’s principal investigator and academic from the School of Medicine of the Universidad de los Andes, Francisca Alcayaga, the activity allowed to deepen its scientific work. “The purpose of BioRed is to discover and validate biomarkers for precise strategies of early diagnosis and new therapeutic targets based on cells or extracellular components focused on perinatal, inflammatory, degenerative pathologies, diseases related to aging and cancer,” she explained. Specifically, IMPACT associate researcher Patricia Luz commented on the advances in the subprogram Mitochondrial intercellular transfer from mesenchymal cells in the physiology and treatment of degenerative and inflammatory conditions. At the same time, the director of the Center for Biomedical Research and Innovation CiiB of the Universidad de los Andes, Federico Batiz, presented the advances in The development of biomarkers to detect and improve neuronal development in newborns.  

In the same way, the principal investigator of IMPACT, Juan Pablo Acevedo, presented the Biomaterials and Biomedical Engineering Program (BioME), which “seeks to improve the personalization and effective application of advanced regenerative medicine therapies by incorporating biosensors, microfluidic technology, 3D biofabrication, intelligent biomaterials, and tissue engineering for tissue-specific targeting, integration with polymeric supports and regenerative induction of biological structures,” he said. In this line, advances in personalized injections for cartilage tissue restoration, bioprocess improvements for cell manufacturing, wearable biosensors, and 3D printing of electroactive smart polymeric nanocomposites for tissue engineering applications and wearable sensors were presented.  

The presentation of the research line in Artificial Intelligence in Bioinformatics and Healthcare (AI Based), was given by the alternate director of the IMPACT Center and leader of the area, René Botnar, who explained that “the objective is to develop, implement and clinically evaluate novel solutions with artificial intelligence (AI) to improve machine learning for prediction-based medical imaging and early diagnosis for clinically relevant applications in joint and perinatal diseases”. In this line, the principal investigator and academic of the University of Chile, Claudio Perez, presented on the advances in the Prediction of diseases and/or conditions associated with pregnancy with AI using basic gestational control data. Similarly, Sebastián Illanes, a physician at the Clínica Universidad de los Andes and academic at the Faculty of Medicine of the same university, presented advances in AI-based solutions for predicting cardiovascular disease risk in patients who have suffered from preeclampsia.  

Finally, IMPACT principal investigator Fernando Figueroa presented on the Translational Clinical Program called Clinical, which “seeks to converge the elements of all programs with translational medicine, generating an interface between biology, engineering and medicine, adding capabilities and frontier knowledge in the design of clinical trials and redefinition of inclusion criteria, incorporating the electronic medical record (EMR), analysis of Big Data using AI and ML, and training of healthcare personnel in the design, monitoring and evaluation of clinical protocols,” he said. In this section, clinical advances in knee osteoarthritis and the future challenges of incorporating exosomes in new cell therapies were presented.  

IMPACT is a scientific and technological center of excellence, funded by the National Agency for Research and Development (ANID) through the Basal Funding Competition 2021. It is led by the Universidad de los Andes, in collaboration with the Pontificia Universidad Católica, Universidad de Chile, Pontificia Universidad Católica de Valparaíso and Universidad de La Frontera. 

Deja una respuesta

Tu dirección de correo electrónico no será publicada. Los campos obligatorios están marcados con *

Link of interest
Subscribe to our Newsletter
© 2023 IMPACT – All rights reserved | Designed by Adtopia